Chaste tree (vitex agnus-castus), or chasteberry, is a plant native to the Mediterranean and Asia. It has been used for centuries in herbal medicine for a variety of hormonal-related and gynaecological conditions. The ancient Greeks and Romans used it to promote spleen health. Traditional Chinese Medicine uses it to support joint heath, eye health and to relieve headaches. Its active constituents consist of flavonoids (castican, orientin and isovitexin), iridoid glycosides (aucubin and agnoside), essential oils (limonene, cineole and sabinene) and essential fatty acids (oleic acid, linolenic acid, palmitic acid and stearic acid).
It is well known for supporting hormones and is used in PMS, PCOS, fertility issues, cyclic mastalgia, hyperprolactinaemia, and modulating the dopaminergic and opioidergic systems. Vitex is also used for menopause symptoms in women and for men, benign prostatic hyperplasia (BPH).