Cleveland HeartLab offers innovative, scientifically proven, and medically relevant biomarkers that are predictive of cardiovascular risk.
The lab offers inflammatory and other advanced biomarker testing that practitioners use in the assessment, management and prevention of heart disease and risks.
Why Look At Advanced Cardiovascular Markers?
Because around 50% of patients experiencing a heart attack or stroke have “normal” cholesterol levels.
The Framingham study in 1948 initially established standard risk factors for heart disease, or atherosclerosis (hardening of the arteries), that include high blood pressure, age, family history, cholesterol, obesity, diabetes, an unhealthy diet and lifestyle factors. However, what we keep learning is that the Framingham risk analysis is limited and fails to accurately detect the presence of heart disease in many individuals.
The risk of developing heart disease has traditionally been assessed by measurement of LDL-C (low-density lipoprotein cholesterol; the carrier of “bad” cholesterol) and HDL-C (high-density lipoprotein cholesterol; the carrier of “good” cholesterol).
If people with levels that are within range are experiencing heat attacks and strokes, something is being missed.Standard lab tests are inadequate. But why do we still use them? Routine cholesterol tests may fail to fully identify those at risk of heart attack or stroke.
Although it is essential to assess your cholesterol levels, adverse cardiac events (such as heart attack, stroke or death) have been associated with inflammation, vulnerable plaque in particular.
Cleveland HeartLab offers inflammatory biomarker testing to help evaluate true cardiovascular risk. These markers include F. This group of tests covers a patient’s biomarker profile which may result from lifestyle concerns (F2-Isoprostanes, Oxidised LDL), to the development of metabolic disease (ADMA/SDMA/ micro albumin, hsCRP) and formation of vulnerable plaque and increased risk of adverse events (Myeloperoxidase, Lipoprotein-associated phospholipase-A2 Lp-PLA2) activity.
Advanced lipid testing also looks at particle size as well as number, lipoprotein (a), TMAO, and other markers.