DUTCH Plus

£389 incl. VAT: £466.80

The DUTCH Plus takes hormone testing to a new level. In addition to sex hormones, their metabolites, the overall diurnal pattern of free cortisol, the DUTCH Plus adds the Cortisol Awakening Response (CAR) to bring another important piece of the HPA axis into focus.

DUTCH-Plus-Female-Sample-Report

DUTCH-Plus-Male-Sample-Report

Functional DX Add Ons

Includes: Cancer markers (CA19-9, CA125, CA15-3). Used for our endobiogenic biology of functions analysis.

Includes: Alk Phos Isoenzymes Can be added to any panel alongside osteocalcin for biology of functions analysis.

Includes: Osteocalcin. Can be added to any panel alongside Alkaline Phosphatase isoenzymes for biology of functions analysis.

Includes: Diamine oxidase (DAO) to assess histamine activity

Includes: GAD65 Antibodies

Includes: NCOV !gG, IgM

Includes: DHEA-sulphate (DHEA-S)

Includes: Prolactin Fertility Add-On

Includes: Oestraidol (E2), Progesterone, SHBG, Testosterone total, FSH, LH, Prolactin. Good for checking fertility and menopause status.

Includes: Oestriadol (E2), Progesterone, PSA-C total, SHBG, Testosterone total, Prolactin, Free PSA, Free and Bioavailable testosterone (calculated values). Fertility Add-On

Includes: Day 21 Progesterone & Oestrogen (E2). Fertility Add-On

Includes: Active B12 & Red Cell Folate (add-on only)

Includes: Serum Copper, Zinc, Selenium, Aluminium

Includes: Anti-Mullerian Hormone (AMH) - Fertility Add-On

Includes: Fatty Acid Profile

Lipoproteins includes: Apolipoprotein A1, Apolipoprotein B1 and Lipoprotein (a)

Includes: H Pylori IgG Antibodies.

Advanced Sugar Includes: C-peptide, Insulin, Fructosamine

EBV IgG and IgM Antibodies includes: Antibodies for Epstein-Barr (glandular fever).

Includes: rT3 + T3 Uptake

Includes: LDH ISO Enzymes

Includes: Cortisol (am - morning draw)

Glucose Includes: HbA1C, Glucose

Includes: Ferritin

RBC Magnesium Includes: Red Cell Magnesium

Includes: Ceruloplasmin

Includes: Reticulocytes

Includes: Fructosamine

CVD Includes: Fibrinogen Activity, Homocysteine

Total Immunoglobulins Include: Total IgE, IgM, IgG

Includes Free Testosterone

Includes LH & FSH

Includes TSH Receptor Antibodies

Thyroid Antibodies Include: Thyroid Peroxidase and Thyroglobulin Antibodies

Vitamins Includes: Folate, Vitamin B12, Vitamin D3

Thyroid Hormones Include:Total T3, Total T4

Product price: £389.00Price incl. VAT: £466.80
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Description

The DUTCH Plus takes hormone testing to a new level. In addition to sex hormones, their metabolites, the overall diurnal pattern of free cortisol, the DUTCH Plus adds the Cortisol Awakening Response (CAR) to bring another important piece of the HPA axis into focus.

Why use DUTCH Plus over DUTCH Complete

A patient might have free cortisol levels within the normal range, but this doesn’t always show things are functioning properly. A blunted or exaggerated CAR allows us to measure stress levels upon waking.

This is useful to assess major depression disorder: A recent study showed that neither the waking nor post-waking cortisol results correlated with Major Depressive Disorder, but the CAR calculation (the change between the first two samples) did. This measurement of the response to waking has independent clinical value showing dysfunction that may be hidden by current testing options.

A low or blunted Cortisol Awakening Response

This can be the result of an underactive HPA axis, excessive psychological burnout, seasonal affective disorder
(SAD), sleep apnoea or poor sleep in general. It can also be due to post-traumatic stress disorder (PTSD), chronic fatigue , or chronic pain.

A blunted CAR has also been associated with systemic hypertension, functional GI diseases, postpartum depression, and autoimmune diseases.

An elevated Cortisol Awakening Response

This can be the result of an overactive HPA axis, anticipatory stress for the day (i.e. due to ongoing job-related stress, relationships, etc.) glycaemic dysregulation, waking with pain, and general depression (not just seasonal affective disorder).

DUTCH Plus includes

Four dried urine samples and five saliva samples. These samples are collected over the course of one day, from waking to bed time. The DUTCH Plus report includes: Metabolites of oestrogens (10, including E1, E2, E3, 2-OHE1, 4-OH-E1, 2-OH-E2, 4-OH-E2, 16-OH-E1, 2-methoxy-E1, 2-methoxy-E2) , androgens (8, including testosterone, DHT and DHEA-S), progesterone (2), cortisol (3), melatonin (6OHMS), 8-OHdG (a useful biomarker for oxidative stress and carcinogenesis, and organic acids (6). The diurnal pattern of Free Cortisol and Cortisone are also provided, including the Cortisol Awakening Response.

 

Postage back to the lab is not included in test prices as the price will vary dependent on method and location.

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